Defying Cystic Fibrosis One Mountain at a Time

Sophie Grace Holmes was born with Cystic Fibrosis (CF). When she was 19, a doctor told her she was going to die within a few years. She set out to prove him wrong, quitting her office job and organizing her life around health and fitness. Sophie is now 27 years old. She is a fitness model, a trainer, a massage therapist and a motivational speaker. She thrives on challenges, and her many accomplishments include completing a 100k and summiting Mt. Kilimanjaro and Mt. Blanc.


Find Sophie on Instagram

Sophie’s Website:

Cystic Fibrosis Trust (

The Cystic Fibrosis Foundation (U.S. org)

Newborn Screening in the U.K.

Newborn Screening in the U.S.

Listen on Spotify, iTunes, SoundCloud, Google Play, or Online. 

Story Reference Points

What is Cystic Fibrosis? @ 1:49

Sophie’s diagnosis with Cystic Fibrosis @ 3:15

Sophie’s turning point at 19 @ 6:19

Sophie’s recent climb of Mt. Blanc  @ 14:36

Social Media and CF @ 19:35

Pioneering better treatment plans for CF with a focus on exercise and nutrition @ 22:54

Sophie’s perspective on bringing a child with CF into the world @ 30:58

Sophie’s perspective on life expectancy and plans for the future @ 33:35

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